rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Synthetic Biology
  name:
    name part: Glieder, Anton.
    role:
      role term: editor.
  name:
    name part: Kubicek, Christian P.
    role:
      role term: editor.
  name:
    name part: Mattanovich, Diethard.
    role:
      role term: editor.
  name:
    name part: Wiltschi, Birgit.
    role:
      role term: editor.
  name:
    name part: Sauer, Michael.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2016
    edition: 1st ed. 2016.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VII, 368 p. 152 illus., 32 illus. in color. online resource.
  abstract: The emerging field of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular processes and whole organisms. This book provides a comprehensive, up-to-date overview of the opportunities and challenges of this complex field of biotechnology, which combines various scientific disciplines. It addresses a broad range of topics, including redesigning complex metabolic pathways, DNA/RNA and protein engineering, as well as novel synthetic biomaterials. It discusses both “bottom up” and “top down” approaches and presents the latest genome engineering tools with predictions about how these could change our way of thinking and working. Since the use of synthetic biology raises a number of ethical questions, a chapter is devoted to public awareness and risk management. The book is of interest to scientists from both academia and industry, as well as PhD students and postdocs working in the field.
  table of contents: Xenobiotic life (artificial cells and cell like structures, biological nanostructures, XNA) -- Novel DNA and RNA (synthetic promoters, riboswitches, small RNAs, ribozymes, adaptamers, DNA walker, DNA machines) -- Expansion of the genetic code and protein building blocks (orthogonal mRNA-ribosome pairs, non canonical amino acids) -- DNA logics and circuit design (including sensors, TALORs, genome rewiring repressilator, oscillator, metabolator, „Multicellular circuits“) -- Protein engineering (directed evolution, domain engineering) -- Synthetic metabolic pathways (engineered pathways, non natural pathways, scaffolding) -- Reengineered chassis cells (minimal organisms, platform hosts, minimal genomes, synthetic genomes) -- In silico simulation and design of complex metabolic and signalling networks -- Novel synthetic biomaterials -- Key methods for synthetic biology (assembly technologies, genome engineering technologies, DNA synthesis, Standardization) -- Public awareness and risk management.
  note: edited by Anton Glieder, Christian P. Kubicek, Diethard Mattanovich, Birgit Wiltschi, Michael Sauer.
  subject:
    topic: Life sciences
  subject:
    topic: Biochemical engineering
  subject:
    topic: Genetic engineering
  subject:
    topic: Systems biology
  subject:
    topic: Biomaterials
  subject:
    topic: Life Sciences
  subject:
    topic: Systems Biology
  subject:
    topic: Biochemical Engineering
  subject:
    topic: Biomaterials
  subject:
    topic: Genetic Engineering
  classification: QH301-705
  classification: 570
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783319227085
  identifier: http://dx.doi.org/10.1007/978-3-319-22708-5
  record info:
    record creation date: 151103
    record change date: 20151103115920.0
    record identifier: 978-3-319-22708-5