rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Alternating Electric Fields Therapy in Oncology
    sub title: A Practical Guide to Clinical Applications of Tumor Treating Fields
  name:
    name part: Wong, Eric T.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 129 p. 52 illus. online resource.
  abstract: This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
  table of contents: 1. Cell Biological Effects of Alternating Electric Fields -- 2. Fundamental Physics of Alternating Electric Fields Therapy -- 3. Biophysical Effects of Alternating Electric Fields -- 4. Computer Simulation of Alternating Electric Fields Therapy -- 5. Response Pattern and Modeling of Tumor-Treating Fields -- 6. Clinical Efficacy of Alternating Electric Fields for Recurrent Glioblastoma -- 7. Alternating Electric Fields in Clinical Practice with Emphasis on PRiDe Registry -- 8. Alternating Electric Fields Therapy for Newly Diagnosed Glioblastoma -- 9. Supportive Care in Patients Using Alternating Electric Fields Therapy -- 10. Future Directions for Alternating Electric Fields.
  note: edited by Eric T. Wong.
  subject:
    topic: Medicine
  subject:
    topic: Neuroradiology
  subject:
    topic: Oncology
  subject:
    topic: Neurology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Oncology
  subject:
    topic: Neurology
  subject:
    topic: Neuroradiology
  classification: RC254-282
  classification: 616.994
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783319305769
  identifier: http://dx.doi.org/10.1007/978-3-319-30576-9
  record info:
    record creation date: 161024
    record change date: 20161024150806.0
    record identifier: 978-3-319-30576-9