rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Melanoma Development
    sub title: Molecular Biology, Genetics and Clinical Application
  name:
    name part: Bosserhoff, Anja K.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    edition: 2nd ed. 2017.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 447 p. 36 illus., 26 illus. in color. online resource.
  abstract: This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.
  table of contents: Clinicopathologic Overview of Melanoma -- Revisiting Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin -- Melanoma Epidemiology -- Melanoma Genetics and Genomics -- Transcriptional Regulation in Melanoma -- MiRNAs in Malignant Melanoma -- Altered Signal Transduction Pathways in Melanoma -- Proteases in Melanoma -- Cell-cell contacts in melanoma and the tumor microenvironment -- Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies -- Senescence -- Melanoma Stem Cells -- The Birth of Malignancy: Embryogenesis and Melanoma -- Tumor Microenvironment for Melanoma Cells -- Melanoma Model Systems -- New Approaches to Signaling -- Immune checkpoint inhibitors in melanoma define a new area in immunotherapy aiming for cure. .
  note: edited by Anja K. Bosserhoff.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783319413198
  identifier: http://dx.doi.org/10.1007/978-3-319-41319-8
  record info:
    record creation date: 170125
    record change date: 20170125073650.0
    record identifier: 978-3-319-41319-8