rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Immune System in Space: Are we prepared?
  name:
    name part: Choukèr, Alexander.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Ullrich, Oliver.
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVII, 127 p. 15 illus., 13 illus. in color. online resource.
  abstract: This book gives insight into the mechanism of the immune system and the influence of the environment on earth. Further, the book explains the changes that occur in our immune system in the absence of gravity and their fundamental consequences. Several limiting factors for human health and performance in microgravity have been clearly identified as an unacceptable risk for long-term and interplanetary flights. Serious concerns arose whether spaceflight-associated immune system dysfunction ultimately precludes the expansion of human presence beyond Earth's orbit. The immune system has undergone many evolutionary steps to cope with a new and changing environment, but `space` has not been evolutionary experienced before. Through endocrine orchestration of cell functions, cell to cell communications and intracellular mechanisms the human body and his immune system have an enormous capacity to adapt and react to altered environmental conditions. Thus, the special sensitivity to altered gravity renders the immune system an ideal biological model system to understand if and how gravity on Earth is required for the normal function of cells and cellular networks. It is one of the most fundamental challenges to find out, if our organism and our cellular machinery are able to live and to adequately perform without the gravity field of Earth. The book is written for immunologists and researchers in human physiology under normal and stressfull conditions.
  table of contents: Immune system in evolution -- The immune system and man – environment interaction from the clinical and from fundamental research perspectives -- The effects of Space and Space like conditions on Immune functions from the clinical and from fundamental perspective -- The upcoming venues: Individualized preventive or therapeutic measure, - In vitro and in vivo tools to measure the efficacy of such measures -- Summary.
  note: by Alexander Choukèr, Oliver Ullrich.
  subject:
    topic: Medicine
  subject:
    topic: Human physiology
  subject:
    topic: Immunology
  subject:
    topic: Aerospace engineering
  subject:
    topic: Astronautics
  subject:
    topic: Biomedicine
  subject:
    topic: Human Physiology
  subject:
    topic: Immunology
  subject:
    topic: Aerospace Technology and Astronautics
  classification: QP34-38
  classification: 612
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: SpringerBriefs in Space Life Sciences
  identifier: 9783319414669
  identifier: http://dx.doi.org/10.1007/978-3-319-41466-9
  record info:
    record creation date: 161021
    record change date: 20161021104504.0
    record identifier: 978-3-319-41466-9