rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Metabolism in Cancer
  name:
    name part: Cramer, Thorsten.
    role:
      role term: editor.
  name:
    name part: A. Schmitt, Clemens.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: IX, 266 p. 31 illus., 25 illus. in color. online resource.
  abstract: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
  table of contents: Metabolic requirements of cellular proliferation -- The role of myc in cancer metabolism -- Metabolic control of inflammation -- Metabolism-targeting therapies -- The role of pH regulation and hypoxia in cancer progression -- Metabolic profiling in breast cancer -- Imaging of tumor metabolism.
  note: edited by Thorsten Cramer, Clemens A. Schmitt.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Oncology
  subject:
    topic: Biochemistry
  subject:
    topic: Cell biology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Oncology
  subject:
    topic: Immunology
  subject:
    topic: Biochemistry, general
  subject:
    topic: Cell Biology
  classification: RC254-282
  classification: 616.994
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Recent Results in Cancer Research, 207
  identifier: 9783319421186
  identifier: http://dx.doi.org/10.1007/978-3-319-42118-6
  record info:
    record creation date: 160824
    record change date: 20160824174403.0
    record identifier: 978-3-319-42118-6