rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular Genetics of Endometrial Carcinoma
  name:
    name part: Hedrick Ellenson, Lora.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 281 p. 32 illus., 31 illus. in color. online resource.
  abstract: This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.
  table of contents: Part 1. Introduction -- 1. Epidemiology and metabolic/hormonal influences -- 2. Pathology -- 3. Clinical behavior and treatment -- Part 2. Molecular Profiling -- 4. Traditional approaches -- 5. Next generation sequencing -- 6. Specific Pathways -- Part 3. Mouse models -- 7. Pten -- 8. Mig-6 -- 9. Lkb -- Part 4. 10. Future Directions -- Index.
  note: edited by Lora Hedrick Ellenson.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Gene expression
  subject:
    topic: Pathology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Gene Expression
  subject:
    topic: Pathology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 943
  identifier: 9783319431390
  identifier: http://dx.doi.org/10.1007/978-3-319-43139-0
  record info:
    record creation date: 161201
    record change date: 20161201145427.0
    record identifier: 978-3-319-43139-0