rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Immunopathology in Toxicology and Drug Development
    sub title: Volume 1, Immunobiology, Investigative Techniques, and Special Studies
  name:
    name part: Parker, George A.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXII, 670 p. 255 illus., 250 illus. in color. online resource.
  abstract: This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system. .
  table of contents: Basic Immunobiology -- Cells of the Immune System -- Signaling and effector molecules in immunity -- Development of immune system organs -- Aging of immune system organs -- Flow cytometry and immunophenotyping in drug development -- Pathology evaluation for detection of immunomodulation -- Enhanced immunohistopathology -- Clinical Pathology Assays in Immunopathology -- Application of immunohistochemistry in toxicologic pathology of the hematolymphoid system -- Morphometry and stereology in immunopathology -- Molecular techniques in immunopathology -- Current issues in developmental immunotoxicity -- The Murine local lymph node assay -- Host Resistance assays for efficacy and immunotoxicology safety evaluations. .
  note: edited by George A. Parker.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Pharmaceutical technology
  subject:
    topic: Medical biochemistry
  subject:
    topic: Pathology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Pathology
  subject:
    topic: Immunology
  subject:
    topic: Pharmaceutical Sciences/Technology
  subject:
    topic: Medical Biochemistry
  classification: RB1-214
  classification: 616.07
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Molecular and Integrative Toxicology
  identifier: 9783319473772
  identifier: http://dx.doi.org/10.1007/978-3-319-47377-2
  record info:
    record creation date: 170328
    record change date: 20171124142741.0
    record identifier: 978-3-319-47377-2