rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Modelling the Toxicity of Nanoparticles
  name:
    name part: Tran, Lang.
    role:
      role term: editor.
  name:
    name part: Bañares, Miguel A.
    role:
      role term: editor.
  name:
    name part: Rallo, Robert.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVII, 352 p. 102 illus., 83 illus. in color. online resource.
  abstract: In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.
  table of contents: Engineered Nanoparticles – Their physico-chemical characteristics and how to measure them -- Measurement -- The Life-Cycle of Engineered Nanoparticles -- From Dose to Response – In vivo Nanoparticle Processing and Potential Toxicity -- From Dose to Response – Literature review od (Q)SAR Modelling of Nanomaterial Toxicity -- Systems biology to support nanomaterial grouping -- Multiscale modelling of bionano interface -- Biological Surface Adsorption Index of Nanomaterials - Modeling Surface Interactions of Nanomaterials with Biomolecules -- Case study I - An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project -- Case study II - Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project -- Case study III – The construction of a nanotoxicity database: the MOD-ENP-TOX experience.
  note: edited by Lang Tran, Miguel A. Bañares, Robert Rallo.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacology
  subject:
    topic: Systems biology
  subject:
    topic: Nanotechnology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Nanotechnology
  subject:
    topic: Systems Biology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 947
  identifier: 9783319477541
  identifier: http://dx.doi.org/10.1007/978-3-319-47754-1
  record info:
    record creation date: 170206
    record change date: 20170206114558.0
    record identifier: 978-3-319-47754-1