rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Kidney Development and Disease
  name:
    name part: Miller, Rachel K.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 372 p. 51 illus., 50 illus. in color. online resource.
  abstract: Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes. .
  table of contents: Part A Model Systems of Kidney Development and Disease -- 1 Drosophila Malpighian tubule: A model for understanding kidney development, function and disease -- 2 Zebrafish pronephros development -- 3 Zebrafish as a model of kidney disease -- 4 Use of Xenopus frogs to study renal development/repair -- Part B Cell Renewal, Differentiation and Fate in Nephrogenesis -- 5 Tissue-specific p53 functions during kidney development -- 6 Growth factor regulation in the nephrogenic zone of the developing kidney -- 7 Development and diseases of the collecting ductsystem -- 8 Origin and function of the renal stroma in health and disease -- Part C Nephron Morphogenesis and Maintenance -- 9 Imaging, analysing and interpreting branching morphogenesis in the developing kidney -- 10 Genetic syndromes affecting kidney development -- 11 Primary cilia in cystic kidney disease -- 12 Inflammation and fibrosis in polycystic kidney disease -- 13 Epithelial to mesenchymal transition (EMT) andendothelial to mesenchymal transition (EndMT): Role and implications in kidney fibrosis.
  note: edited by Rachel K. Miller.
  subject:
    topic: Life sciences
  subject:
    topic: Molecular biology
  subject:
    topic: Nephrology
  subject:
    topic: Cell biology
  subject:
    topic: Developmental biology
  subject:
    topic: Life Sciences
  subject:
    topic: Developmental Biology
  subject:
    topic: Molecular Medicine
  subject:
    topic: Nephrology
  subject:
    topic: Cell Biology
  classification: QH491
  classification: 571.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Results and Problems in Cell Differentiation, 60
  identifier: 9783319514369
  identifier: http://dx.doi.org/10.1007/978-3-319-51436-9
  record info:
    record creation date: 170413
    record change date: 20170413115635.0
    record identifier: 978-3-319-51436-9