rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular Basis for Mitochondrial Signaling
  name:
    name part: Rostovtseva, Tatiana K.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 386 p. 61 illus., 54 illus. in color. online resource.
  abstract: This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.
  table of contents: From the Contents: Mitochondrial Calcium Signaling -- Systems approaches to mitochondrial calcium signaling -- The mitochondrial Calcium Uniporter: Molecular Composition And Physiological Role -- Molecular Mechanisms of Mitochondrial Ca2+ Uptake -- Ca2+ uniporter and male fertility.
  note: edited by Tatiana K. Rostovtseva.
  subject:
    topic: Physics
  subject:
    topic: Cell cycle
  subject:
    topic: Apoptosis
  subject:
    topic: Physics
  subject:
    topic: Biological and Medical Physics, Biophysics
  subject:
    topic: Cell Cycle Analysis
  subject:
    topic: Apoptosis
  classification: QH505
  classification: 571.4
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Biological and Medical Physics, Biomedical Engineering
  identifier: 9783319555393
  identifier: http://dx.doi.org/10.1007/978-3-319-55539-3
  record info:
    record creation date: 170515
    record change date: 20170515090712.0
    record identifier: 978-3-319-55539-3