rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cell Division Machinery and Disease
  name:
    name part: Gotta, Monica.
    role:
      role term: editor.
  name:
    name part: Meraldi, Patrick.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 235 p. 33 illus., 32 illus. in color. online resource.
  abstract: This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases.
  table of contents: 1.Meiotic divisions: no place for gender equality -- 2.Consequences of centrosome dysfunction during brain development -- 3.Dividing with extra centrosomes: a double edged sword for cancer cells -- 4.Kinetochore malfunction in human pathologies -- 5.The elephant in the room: the role of microtubules in cancer -- 6.Clinical development of anti-mitotic drugs in cancer -- 7.Mitotic dysfunction associated with aging hallmarks -- 8.Unbalanced Growth, Senescence and Aging -- 9.The spindle orientation machinery beyond mitosis: when cell specialization demands polarization.
  note: edited by Monica Gotta, Patrick Meraldi.
  subject:
    topic: Life sciences
  subject:
    topic: Cancer research
  subject:
    topic: Cell cycle
  subject:
    topic: Cell physiology
  subject:
    topic: Life Sciences
  subject:
    topic: Cell Cycle Analysis
  subject:
    topic: Cell Physiology
  subject:
    topic: Cancer Research
  classification: QH573-671
  classification: QR73.7
  classification: 571.84
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 1002
  identifier: 9783319571270
  identifier: http://dx.doi.org/10.1007/978-3-319-57127-0
  record info:
    record creation date: 170609
    record change date: 20170616161949.0
    record identifier: 978-3-319-57127-0