rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: G-Protein-Coupled Receptor Dimers
  name:
    name part: Herrick-Davis, Katharine.
    role:
      role term: editor.
  name:
    name part: Milligan, Graeme.
    role:
      role term: editor.
  name:
    name part: Di Giovanni, Giuseppe.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVII, 501 p. 70 illus., 58 illus. in color. online resource.
  abstract: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.
  table of contents: Part I. Introduction -- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization -- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer -- 5. Extreme Vetting of Dopamine Receptor Oligomerization -- 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers -- 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses -- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs -- 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers -- 19. Heteromers form Novel Signaling Complexes -- 20. Heteroreceptor Complexes Implicated in Parkinson’s Disease.
  note: edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Biomedicine
  subject:
    topic: Neurosciences
  classification: RC321-580
  classification: 612.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: The Receptors ; 33
  identifier: 9783319601748
  identifier: http://dx.doi.org/10.1007/978-3-319-60174-8
  record info:
    record creation date: 170831
    record change date: 20170831184326.0
    record identifier: 978-3-319-60174-8