rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Viruses, Genes, and Cancer
  name:
    name part: Hunter, Eric.
    role:
      role term: editor.
  name:
    name part: Bister, Klaus.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 221 p. online resource.
  abstract: This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.
  table of contents: Exchange of Genetic Sequences Between Viruses and Host -- Virus-Host Gene Interactions that Define HIV Disease Progression -- Sequencing the Biology of Entry: The Retroviral env Gene -- Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic Diseases -- MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer -- Oncogenic Roles of the PI3K/AKT/mTOR Axis -- MicroRNAs and Cancer -- The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the P53 Gene.
  note: edited by Eric Hunter, Klaus Bister.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Virology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Virology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Current Topics in Microbiology and Immunology, 407
  identifier: 9783319618043
  identifier: http://dx.doi.org/10.1007/978-3-319-61804-3
  record info:
    record creation date: 170828
    record change date: 20170828141709.0
    record identifier: 978-3-319-61804-3