rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Amorphous Drugs
    sub title: Benefits and Challenges
  name:
    name part: Rams-Baron, Marzena.
    role:
      role term: creator
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Jachowicz, Renata.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Boldyreva, Elena.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Zhou, Deliang.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Jamroz, Witold.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Paluch, Marian.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2018
    edition: 1st ed. 2018.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: IX, 230 p. 69 illus., 48 illus. in color. online resource.
  abstract: This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products. .
  table of contents: Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.
  note: by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch.
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Pharmaceutical technology
  subject:
    topic: Phase transitions (Statistical physics)
  subject:
    topic: Thermodynamics
  subject:
    topic: Ceramics
  subject:
    topic: Glass
  subject:
    topic: Composites (Materials)
  subject:
    topic: Composite materials
  subject:
    topic: Biomedical engineering
  subject:
    topic: Medicinal Chemistry
  subject:
    topic: Pharmaceutical Sciences/Technology
  subject:
    topic: Phase Transitions and Multiphase Systems
  subject:
    topic: Thermodynamics
  subject:
    topic: Ceramics, Glass, Composites, Natural Materials
  subject:
    topic: Biomedical Engineering and Bioengineering
  classification: RS400-431
  classification: 615.19
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783319720029
  identifier: https://doi.org/10.1007/978-3-319-72002-9
  record info:
    record creation date: 180209
    record change date: 20191022022833.0
    record identifier: 978-3-319-72002-9