rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Fibrosis in Disease
    sub title: An Organ-Based Guide to Disease Pathophysiology and Therapeutic Considerations
  name:
    name part: Willis, Monte S.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: Yates, Cecelia C.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: Schisler, Jonathan C.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2019
    edition: 1st ed. 2019.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIX, 471 p. 62 illus., 59 illus. in color. online resource.
  abstract: This book serves as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. It provides new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It also highlights the many new areas of therapeutic investigation currently underway. Lastly, it touches upon newly emerging fields and investigates the role of fibrosis in macular degeneration and cancer metastasis. Chapters are written by established experts in their fields, including clinicians, cardiologists, cardiovascular surgeons, pathologists, general practitioners, and translational biomedical researchers in a wide range of disciplines. However, the material also applies to a broader audience, including medical residents, fellows, and M.D. or Ph.D. post-doctoral research fellows. While comprehensive, this book presents the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience.
  table of contents: Introduction -- The Role of Chemokines in Fibrotic dermal remodeling and wound healing -- Fibrosis and immune dysregulation in systemic sclerosis -- Macrophage Plasticity in Skin Fibrosis -- Fibrotic Signaling in the Lung -- Pulmonary Matrikines: Origin, Function and Contribution to Fibrotic and Non-Fibrotic Lung Disease -- The Role of Mast Cells in the Pathophysiology of Pulmonary Fibrosis -- PERICYTES AND T CELLS IN LUNG INJURY AND FIBROPROLIFERATION -- Emerging Therapeutic Targets and Therapies in Idiopathic Pulmonary Fibrosis -- Dynamic reciprocity- the role of the extracellular matrix microenvironment in amplifying and sustaining pathological lung fibrosis -- Fibrotic Signaling in Cardiomyopathies -- WNT SIGNALING AND CARDIAC FIBROSIS -- Matrix metalloproteinase-9-dependent mechanisms of reduced contractility and increased stiffness in the aging heart -- Using peptidomics to identify extracellular matrix-derived peptides as novel therapeutics for cardiac disease -- Vascular Fibrosis and Disease -- Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment -- Tipping the balance from angiogenesis to fibrosis in chronic kidney disease -- Fibrotic Remodeling in Exudative (Wet) Macular Degeneration.
  note: edited by Monte S. Willis, Cecelia C. Yates, Jonathan C. Schisler.
  subject:
    topic: Pathology
  subject:
    topic: Cardiology
  subject:
    topic: Pathology
  subject:
    topic: Cardiology
  classification: RB1-214
  classification: 616.07
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Molecular and Translational Medicine
  identifier: 9783319981437
  identifier: https://doi.org/10.1007/978-3-319-98143-7
  record info:
    record creation date: 181110
    record change date: 20190620081207.0
    record identifier: 978-3-319-98143-7