rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Lessons on Caffeine, Cannabis & Co
    sub title: Plant-derived Drugs and their Interaction with Human Receptors
  name:
    name part: Böttger, Angelika.
    role:
      role term: creator
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Vothknecht, Ute.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Bolle, Cordelia.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: Wolf, Alexander.
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2018
    edition: 1st ed. 2018.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 217 p. 69 illus., 50 illus. in color. online resource.
  abstract: This textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike.
  table of contents: Introduction: Plant secondary metabolites and their general function in plants -- Historical and current perspective -- Medicinal use -- Recreational use -- General overview over biosynthesis pathways of plant secondary metabolites -- Drugs affecting GPCR: GPCRs in plants and animals -- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin -- Opiate receptors - morphine, salvinorin A -- Cannabinoid receptors - THC -- Muscarinergic acetylcholin receptor - muscarin, atropine -- Adenosine receptor - caffeine -- Drugs affecting ion channels: Ligand and voltage activated channels -- Nicotinic acetylcholin receptor - Nicotine, Curare -- GABAA/C-receptor - Muscimol, thujone -- ionotropic Glycine receptor - Strychnine -- ionotropic Glutamate receptor - ibogtenic acid, kainic acid -- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin -- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants -- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan) -- Topoisomerase - camptothecin, etoposide -- G2/M phase arrest, apoptosis - curcubitacin, triptolide.
  note: by Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf.
  subject:
    topic: Pharmacology
  subject:
    topic: Plant biochemistry
  subject:
    topic: Science education
  subject:
    topic: Biotechnology
  subject:
    topic: Cancer research
  subject:
    topic: Molecular biology
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Plant Biochemistry
  subject:
    topic: Science Education
  subject:
    topic: Biotechnology
  subject:
    topic: Cancer Research
  subject:
    topic: Molecular Medicine
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Learning Materials in Biosciences
  identifier: 9783319995465
  identifier: https://doi.org/10.1007/978-3-319-99546-5
  record info:
    record creation date: 181229
    record change date: 20191024082343.0
    record identifier: 978-3-319-99546-5