rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Neuroblastoma
  name:
    name part: Cheung, Nai-Kong V.
    role:
      role term: editor.
  name:
    name part: Cohn, Susan L.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XV, 300 p. 51 illus., 21 illus. in color. online resource.
  abstract: Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.
  table of contents: Epidemiology -- Screening for Neuroblastoma -- Genetics -- Molecular Cytogenetics -- Molecular and Developmental Biology of Neuroblastoma -- Cellular Heterogeneity -- Clinical Presentation -- Pathology of Peripheral Neuroblastic Tumors -- Molecular Pathology of Neuroblastic Tumors Based on Genome-wide Expression Analysis -- Anatomic and Functional Imaging -- Treatment of Neuroblastoma -- Treatment of Relapsed and Refractory Neuroblastoma -- Management of Neurologic Complications -- Immunology and Immunotherapy -- Differentiation and Retinoids -- Angiogenesis -- Experimental Therapeutics and Preclinical Models -- Late Effects of Treatment -- Perspectives and Future Directions.
  note: edited by Nai-Kong V. Cheung, Susan L. Cohn.
  subject:
    topic: Medicine
  subject:
    topic: Oncology
  subject:
    topic: Neurology
  subject:
    topic: Pediatrics
  subject:
    topic: Pediatric surgery
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Oncology
  subject:
    topic: Pediatrics
  subject:
    topic: Neurology
  subject:
    topic: Pediatric Surgery
  classification: RC254-282
  classification: 616.994
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Pediatric Oncology
  identifier: 9783540266167
  identifier: http://dx.doi.org/10.1007/b137762
  record info:
    record creation date: 100301
    record change date: 20151204160910.0
    record identifier: 978-3-540-26616-7