rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular Parameters Indicating Adaptation to Mechanical Stress in Fibrous Connective Tissue
  name:
    name part: Milz, Stefan.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Benjamin, Michael.
    role:
      role term: author.
  name:
    name part: Putz, Reinhard.
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VI, 74 p. online resource.
  abstract: The present study pursues the hypothesis that local compressive force and the occurrence of cartilage-specific transformation processes within tendons and ligaments are directly correlated. In selected anatomical samples of human origin the distribution pattern of certain components of the extracellular matrix is assessed. Investigations are carried out at the extensor tendons of toes and fingers, at the transverse ligament of the atlas, at the transverse ligament of the acetabulum, and at the tendon of the superior oblique muscle and its trochlea. The molecular components of the extracellular matrix are detected with standardized immunohistochemical methods. The results show that certain molecules only occur due to compressive stress, others due to tensile stress. The molecular spectrum of the extracellular matrix allows qualifying conclusions to the mechanical situation of a given part of the tissue. The spatial expansion of the fibrocartilaginous adaptation zones in tendons and ligaments roughly corresponds with the zones subjected to compressive force; tensile stress alone does not result in a production of fibrocartilage.
  table of contents: Introduction: Preliminary remarks; Adaptation of connective and supportive tissues to their respective functions; Parameters of functional adaptation -- Study aim: Fundamental considerations; Structure of the present study; Questions -- Anatomical structures investigated: Extensor tendons of the toes in the region of the proximal interphalangeal joint (PIP); Extensor tendons of the hand in the region of the MCP joint; The transverse ligament of the atlas; The transverse ligament of the acetabulum; Tendon and trochlea of the superior oblique muscle -- Materials and methods: Materials; Methodology of the immunohistochemical investigation -- Results: Extensor tendons of the toes; Extensor tendons of the hand in the region of the MCP joint; The transverse ligament of the atlas -- Discussion: Discussion of the method; Discussion of the present study's structure; Discussion of results; Conclusions -- Summary -- Bibliography -- Subject Index.
  note: by Stefan Milz, Michael Benjamin, Reinhard Putz.
  subject:
    topic: Medicine
  subject:
    topic: Biomedicine
  subject:
    topic: Biomedicine general
  classification: R-RZ
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Anatomy Embryology and Cell Biology, 178
  identifier: 9783540278320
  identifier: http://dx.doi.org/10.1007/3-540-27832-X
  record info:
    record creation date: 100301
    record change date: 20131005114056.0
    record identifier: 978-3-540-27832-0