rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Systems Biology
    sub title: Applications and Perspectives
  name:
    name part: Bringmann, P.
    role:
      role term: editor.
  name:
    name part: Butcher, E. C.
    role:
      role term: editor.
  name:
    name part: Parry, G.
    role:
      role term: editor.
  name:
    name part: Weiss, B.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2007
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 177 p. online resource.
  abstract: Systems biology has emerged as a highly interdisciplinary ?eld that has created broad enthusiasm in the scienti?c community. Systems biology is in vogue because of its potential to revolutionize not only biology but also medicine. Developments are anticipated that will change how we think about disease and how we approach therapeutic intervention. Perhaps the boldest vision of this future is presented by Dr. Leroy Hood, President of the Institute for Systems Biology in Seattle. He has been a protagonist and the main driving force of the underlying concept. - cording to Dr. Hood, systems biology will make possible a new era of medical care comprising predictive, preventive, personalized and part- ipatory (P4) medicine. While this vision appears futuristic, it has enticed both academic scienti?c communities and pharmaceutical industry R&D organizations. Systems biology ultimately attempts to understand biological s- tems at the molecular level. Examples of such systems are subcellular regulatory circuits with all their components, cells, organs, as well as - tire organisms. Over the past decade, technologies have been developed that enable systems-level interrogations, e.g., gene expression pro?ling, proteomics, and metabonomics, to name a few. Scientists have used such platforms to accumulate a tremendous amount of data. Although we have learned a great deal by collecting such detailed information, it seems our understanding has not similarly increased.
  table of contents: RNAi Applications in Target Validation -- Does the Serum Peptidome Reveal Hemostatic Dysregulation? -- Systems Biology: New Paradigms for Cell Biology and Drug Design -- The Theory of Biological Robustness and Its Implication in Cancer -- Network Genomics -- A Plea for More Theory in Molecular Biology -- Applying a Causal Framework to System Modeling -- Can Cell Systems Biology Rescue Drug Discovery?.
  note: edited by P. Bringmann, E. C. Butcher, G. Parry, B. Weiss.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Endocrinology
  subject:
    topic: Cell biology
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Cell Biology
  subject:
    topic: Endocrinology
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Ernst Schering Research Foundation Workshop, 61
  identifier: 9783540313397
  identifier: http://dx.doi.org/10.1007/978-3-540-31339-7
  record info:
    record creation date: 100301
    record change date: 20151204155245.0
    record identifier: 978-3-540-31339-7