rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Microbial Protein Toxins
  name:
    name part: Schmitt, Manfred J.
    role:
      role term: editor.
  name:
    name part: Schaffrath, Raffael.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2005
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 237 p. 41 illus., 6 illus. in color. online resource.
  abstract: Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.
  table of contents: Diphtheria Toxin, Diphtheria-related Fusion Protein Toxins, and the Molecular Mechanism of Their Action Against Eukaryotic Cells -- Anthrax Toxin and Genetic Aspects Regulating its Expression -- Shiga Toxins and Their Mechanisms of Cell Entry -- Cholera Toxin: Mechanisms of Entry Into Host Cells -- ExoU: A Cytotoxin Delivered by the Type III Secretion System of Pseudomonas aeruginosa -- Staphylococcal Alpha-toxin -- S. cerevisiae K28 Toxin - a Secreted Virus Toxin of the A/B Family of Protein Toxins -- Kluyveromyces lactis Zymocin and Other Plasmid-encoded Yeast Killer Toxins -- The Ustilago maydis Killer Toxins -- Zygocin – a Monomeric Protein Toxin Secreted by Virus-infected Zygosaccharomyces bailii -- Acidophilic Structure and Killing Mechanism of the Pichia farinosa Killer Toxin SMKT -- Ricin: Structure, Synthesis, and Mode of Action.
  note: edited by Manfred J. Schmitt, Raffael Schaffrath.
  subject:
    topic: Life sciences
  subject:
    topic: Medical microbiology
  subject:
    topic: Biochemistry
  subject:
    topic: Cell biology
  subject:
    topic: Microbiology
  subject:
    topic: Life Sciences
  subject:
    topic: Microbiology
  subject:
    topic: Medical Microbiology
  subject:
    topic: Biochemistry, general
  subject:
    topic: Cell Biology
  classification: QR1-502
  classification: 579
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Topics in Current Genetics, 11
  identifier: 9783540314554
  identifier: http://dx.doi.org/10.1007/b94860
  record info:
    record creation date: 100806
    record change date: 20151204152936.0
    record identifier: 978-3-540-31455-4