rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Alzheimer: 100 Years and Beyond
  name:
    name part: Jucker, Mathias.
    role:
      role term: editor.
  name:
    name part: Beyreuther, Konrad.
    role:
      role term: editor.
  name:
    name part: Haass, Christian.
    role:
      role term: editor.
  name:
    name part: Nitsch, Roger M.
    role:
      role term: editor.
  name:
    name part: Christen, Yves.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2006
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXXIV, 544 p. 195 illus., 143 illus. in color. online resource.
  abstract: Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
  table of contents: Alois Alzheimer -- Concerning a unique disease of the cerebral cortex -- The history of Alois Alzheimer’s first case Auguste D. -- Alois Alzheimer and the beginnings of research into Alzheimer’s disease -- Alois Alzheimer and the myth of the pioneer -- The beginning of modern research -- Alzheimer’s Disease at mid-Century (1927–1977) and a little more -- A chapter in the development on Alzheimer’s disease research -- Anatomy & Neuropsychology -- Anatomical changes underlying dementia in Alzheimer’s disease -- Staging of cortical neurofibrillary inclusions of the Alzheimer’s type -- Of stains and brains: a brief account of how microscopic and clinical observations contributed to the understanding of Alzheimer’s disease -- Presenile forms of Alzheimer’s disease in 2006 -- Cholinergic Deficit -- The cholinergic deficit in Alzheimer’s disease -- Acetylcholine in AD: Expectations meet reality -- Amyloid and Genetics -- The Discovery of ? Amyloid -- Pathways to the discovery of the neuronal origin and proteolytic biogenesis of A? amyloid of Alzheimer’s disease -- The Amyloid Hypothesis: history and alternatives -- Segregation of a missense mutation in the amyloid ?-protein precursor gene with familial Alzheimer’s disease -- From the amyloid ? protein (A4) to isolation of the first Alzheimer’s disease gene: amyloid ? (A4) precursor protein (APP) -- Commentary on “Correlative memory deficits, A? elevation, and amyloid plaques in transgenic mice” -- Vision for the future -- PS1, PS2, and APP mutations that cause Alzheimer’s disease increase A?42 -- Amyloid precursor protein, Alzheimer’s disease, and Down’s syndrome -- Catabolism of amyloid ? peptide and pathogenesis of sporadic Alzheimer’s disease: towards understanding the underlying mechanisms -- Synaptic activity, amyloid-? and Alzheimer’s disease -- Molecular pathogenesis of Alzheimer’s disease in human peripheral cells: platelets show it all! -- The neuronal origin hypothesis of cerebral amyloid angiopathy -- A neuropat…
  note: edited by Mathias Jucker, Konrad Beyreuther, Christian Haass, Roger M. Nitsch, Yves Christen.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Biomedicine
  subject:
    topic: Neurosciences
  classification: RC321-580
  classification: 612.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Research and Perspectives in Alzheimer’s Disease
  identifier: 9783540376521
  identifier: http://dx.doi.org/10.1007/978-3-540-37652-1
  record info:
    record creation date: 100301
    record change date: 20150519191642.0
    record identifier: 978-3-540-37652-1