rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Progestins and the Mammary Gland
    sub title: From Basic Science to Clinical Applications
  name:
    name part: Conneely, O.
    role:
      role term: editor.
  name:
    name part: Otto, C.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2008
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVII, 199 p. online resource.
  abstract: Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.
  table of contents: Dynamic Regulation of Progesterone Receptor Activity in Female Reproductive Tissues -- Steroid Receptor Coactivator 2: An Essential Coregulator of Progestin-Induced Uterine and Mammary Morphogenesis -- Inhibition of Mammary Tumorigenesis by Estrogen and Progesterone in Genetically Engineered Mice -- Estrogens, Progestins, and Risk of Breast Cancer -- Mammary Development, Carcinomas and Progesterone: Role of Wnt Signalling -- Progesterone Signaling in Mammary Gland Development -- Progesterone Receptor Isoforms in Normal and Malignant Breast -- In Vivo Characterization of Progestins with Reduced Non-genomic Activity In Vitro -- In Vitro and In Vivo Characterization of a Novel Nonsteroidal, Species-Specific Progesterone Receptor Modulator, PRA-910.
  note: edited by O. Conneely, C. Otto.
  subject:
    topic: Life sciences
  subject:
    topic: Molecular biology
  subject:
    topic: Pharmacology
  subject:
    topic: Endocrinology
  subject:
    topic: Reproductive medicine
  subject:
    topic: Animal genetics
  subject:
    topic: Life Sciences
  subject:
    topic: Animal Genetics and Genomics
  subject:
    topic: Reproductive Medicine
  subject:
    topic: Endocrinology
  subject:
    topic: Molecular Medicine
  subject:
    topic: Pharmacology/Toxicology
  classification: QH432
  classification: 591.35
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Ernst Schering Foundation Symposium Proceedings, 2007/1
  identifier: 9783540734932
  identifier: http://dx.doi.org/10.1007/978-3-540-73493-2
  record info:
    record creation date: 100301
    record change date: 20151204184910.0
    record identifier: 978-3-540-73493-2