rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Specialization and Complementation of Humoral Immune Responses to Infection
  name:
    name part: Manser, Tim.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2008
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 162 p. online resource.
  abstract: In recent years the results of past studies on T cell dependent and T cell independent antibody responses have coalesced with discoveries regarding the roles of various primary B cell subsets and components of the innate immune system in conferring resistance to infectious pathogens. As a consequence, a new and more complete understanding of how antibody-mediated resistance to pathogens is elaborated has emerged. The recent explosion of knowledge of Toll-like receptor specificity and function has further embellished this understanding. It is now clear that there is not only extensive overlap and cross-complementarity in the action of innate and adaptive immune systems, but also specialization of function of the various B cell subsets and the types of antibodies they produce. This synergistic interaction of multiple components of these systems is perhaps best exemplified in antibody responses to bacteria. Contributions to this monograph were chosen to highlight this new perspective on antibody responses to infection, as well as to convey its practical implications, such as for contemporary vaccine design.
  table of contents: Pattern Recognition by B Cells: The Role of Antigen Repetitiveness Versus Toll-Like Receptors -- The Multifunctional Role of Antibodies in the Protective Response to Bacterial T Cell-Independent Antigens -- B Cell Lineage Contributions to Antiviral Host Responses -- The Important and Diverse Roles of Antibodies in the Host Response to Borrelia Infections -- A Distinct Role for B1b Lymphocytes in T Cell-Independent Immunity -- Secretory Immunity Following Mutans Streptococcal Infection or Immunization.
  note: edited by Tim Manser.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Virology
  subject:
    topic: Biomedicine
  subject:
    topic: Immunology
  subject:
    topic: Virology
  classification: QR180-189.5
  classification: 616.079
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Current Topics in Microbiology and Immunology, 319
  identifier: 9783540739005
  identifier: http://dx.doi.org/10.1007/978-3-540-73900-5
  record info:
    record creation date: 100301
    record change date: 20151204161418.0
    record identifier: 978-3-540-73900-5