rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular Imaging
    sub title: Radiopharmaceuticals for PET and SPECT
  name:
    name part: Vallabhajosula, Shankar.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2009
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XX, 372 p. 221 illus., 139 illus. in color. online resource.
  abstract: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
  table of contents: Molecular Imaging: Introduction -- Science of Atomism: A Brief History -- Atoms and Radiation -- Radioactivity -- Production of Radionuclides -- PET and SPECT Scanners -- Chemistry: Basic Principles -- Cell and Molecular Biology -- Radiopharmaceuticals -- Chemistry of Radiohalogens (F, Br. and I) -- Chemistry of Organic Radionuclides (C, N, and O) -- Chemistry of Metal Radionuclides (Rb, Ga, In, Y, Cu and Tc) -- Qouality Control of PET Rediopharmaceuticals -- Pharmacokinetics and Modeling -- Molecular Imaging in Oncology -- Molecular Imaging in Neurology and Psychiatry -- Molecular Imaging in Cardiology -- Molecular Imaging of Gene Expression and Cell Trafficking -- Radiation Dosimetry and Protection -- Radiopharmaceuticals: Drug Development and Regulatory Issues.
  note: by Shankar Vallabhajosula.
  subject:
    topic: Medicine
  subject:
    topic: Radiology
  subject:
    topic: Nuclear medicine
  subject:
    topic: Cardiology
  subject:
    topic: Oncology
  subject:
    topic: Neurology
  subject:
    topic: Pathology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Nuclear Medicine
  subject:
    topic: Imaging / Radiology
  subject:
    topic: Pathology
  subject:
    topic: Oncology
  subject:
    topic: Cardiology
  subject:
    topic: Neurology
  classification: R895-920
  classification: 616.07548
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783540767350
  identifier: http://dx.doi.org/10.1007/978-3-540-76735-0
  record info:
    record creation date: 100301
    record change date: 20151204150830.0
    record identifier: 978-3-540-76735-0