rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Marine Toxins as Research Tools
  name:
    name part: Fusetani, Nobuhiro.
    role:
      role term: editor.
  name:
    name part: Kem, William.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2009
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 259 p. online resource.
  abstract: Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.
  table of contents: Marine Toxins: An Overview -- Conotoxins: Molecular and Therapeutic Targets -- Sodium Channel Inhibiting Marine Toxins -- Sea Anemone Toxins Affecting Potassium Channels -- Ligands for Ionotropic Glutamate Receptors -- Marine Toxins Potently Affecting Neurotransmitter Release -- Toxins Affecting Actin Filaments and Microtubules -- Carcinogenic Aspects of Protein Phosphatase 1 and 2A Inhibitors.
  note: edited by Nobuhiro Fusetani, William Kem.
  subject:
    topic: Chemistry
  subject:
    topic: Pharmacology
  subject:
    topic: Biotechnology
  subject:
    topic: Environmental engineering
  subject:
    topic: Chemistry
  subject:
    topic: Biotechnology
  subject:
    topic: Environmental Engineering/Biotechnology
  subject:
    topic: Pharmacology/Toxicology
  classification: TP248.13-248.65
  classification: 660.6
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Progress in Molecular and Subcellular Biology, 46
  identifier: 9783540878957
  identifier: http://dx.doi.org/10.1007/978-3-540-87895-7
  record info:
    record creation date: 100301
    record change date: 20151125162149.0
    record identifier: 978-3-540-87895-7