rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Double [3+2] Photocycloaddition Reaction
  name:
    name part: Woolford, Jason A.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 184 p. online resource.
  abstract: Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to contruct fenstrane frameworks. The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.
  table of contents: Introduction and background -- Discovery of the double [3+2] photocycloaddition -- A brief discussion on fenestranes -- Investigation of the double [3+2] photocycloaddition reaction for the synthesis of fenestranes -- Attempted synthesis of a “criss-cross” double [3+2] photocycloadduct -- Attempts toward the synthesis of alternative structures via the double[3+2] photocycloaddition -- Conclusion -- Experimental -- References -- Appendix I.
  note: by Jason A. Woolford.
  subject:
    topic: Chemistry
  subject:
    topic: Analytical chemistry
  subject:
    topic: Organic chemistry
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Chemistry
  subject:
    topic: Organic Chemistry
  subject:
    topic: Medicinal Chemistry
  subject:
    topic: Analytical Chemistry
  classification: QD415-436
  classification: 547
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Springer Theses
  identifier: 9783642228605
  identifier: http://dx.doi.org/10.1007/978-3-642-22860-5
  record info:
    record creation date: 110829
    record change date: 20151204161046.0
    record identifier: 978-3-642-22860-5