rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Myeloproliferative Neoplasms
    sub title: Critical Concepts and Management
  name:
    name part: Barbui, Tiziano.
    role:
      role term: editor.
  name:
    name part: Tefferi, Ayalew.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 240p. 22 illus., 13 illus. in color. online resource.
  abstract: Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs. This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.
  table of contents: Biology -- Gerneral Issues in the Management of MPNs -- Specific Issues of Treatment in PV and ET -- Treatment of PMF -- Research Issues and Perspectives.
  note: edited by Tiziano Barbui, Ayalew Tefferi.
  subject:
    topic: Medicine
  subject:
    topic: Internal medicine
  subject:
    topic: Hematology
  subject:
    topic: Oncology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Hematology
  subject:
    topic: Internal Medicine
  subject:
    topic: Oncology
  classification: RB45
  classification: 616.15
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Hematologic Malignancies
  identifier: 9783642249891
  identifier: http://dx.doi.org/10.1007/978-3-642-24989-1
  record info:
    record creation date: 120109
    record change date: 20150519192355.0
    record identifier: 978-3-642-24989-1