rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Novel Antischizophrenia Treatments
  name:
    name part: Geyer, Mark A.
    role:
      role term: editor.
  name:
    name part: Gross, Gerhard.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 458 p. online resource.
  abstract: This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
  table of contents: Preface -- Clinical instruments to evaluate and guide treatment in schizophrenia -- Cognitive deficits in schizophrenia- Muscarinic mechanisms in psychotic disorders -- Nicotinic mechanisms in psychotic disorders -- GABAergic circuits in schizophrenia: targets for new treatments in schizophrenia -- Inhibitors of glycine transport as potential new treatments in schizophrenia -- The role of glutamate in schizophrenia -- Metabotropic glutamate receptors as targets for new treatments in schizophrenia -- 5-HT2C agonism as a principle for new treatments in schizophrenia.- The role of dopamine D3 receptors for antipsychotic activity and cognitive functions -- Phosphodiesterase inhibitors as potential new treatments in schizophrenia -- Disease modifying approaches to schizophrenia -- A novel therapeutic strategy: medication-enhancement of cognitive therapies in schizophrenia -- Transgenic animals reflecting aspects of schizophrenia -- Behavioral animal models of pro-cognitive treatments for schizophrenia. .
  note: edited by Mark A. Geyer, Gerhard Gross.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacy
  subject:
    topic: Pharmacology
  subject:
    topic: Psychopharmacology
  subject:
    topic: Biological psychology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Pharmacy
  subject:
    topic: Psychopharmacology
  subject:
    topic: Biological Psychology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Handbook of Experimental Pharmacology, 213
  identifier: 9783642257582
  identifier: http://dx.doi.org/10.1007/978-3-642-25758-2
  record info:
    record creation date: 121009
    record change date: 20151204165420.0
    record identifier: 978-3-642-25758-2