http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Coarse-Grained Modelling of DNA and DNA Self-Assembly
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker.
Statistical Physics, Dynamical Systems and Complexity
Soft and Granular Matter, Complex Fluids and Microfluidics
Springer Theses, Recognizing Outstanding Ph.D. Research