rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Studying Cell Metabolism and Cell Interactions Using Microfluidic Devices Coupled with Mass Spectrometry
  name:
    name part: Wei, Huibin.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XVI, 104 p. online resource.
  abstract: This thesis describes a new approach for cell analysis by the rapid developing microfluidic technology. The nominee has made great contributions to develop a new analysis platform which combined microfluidic devices with mass spectrometry to determine the trace compounds secreted by cells. Based on this analysis platform, she studied the specific cell secreting behaviors under controlled microenvironment, of which the secretion compounds were qualified and semi-quantified by mass spectrometry. A novel cell sorting device integrated homogenous porous PDMS membrane was invented to classify cells from real samples based on the size difference. The nominee further studied the signal transmission between different cells, and the signal chemicals were qualitative and quantitative monitored by the analysis platform. This indicates the potential significant application of the new cell analysis platform in medicine screening and early diagnosis.
  table of contents: Introduction -- Analysis of Herbicides on a Single C30 Bead via the Platform Combined Microfluidic Device with ESI-Q-TOF-MS -- Monitoring of Glutamate Release from Neuronal Cell Based on the Analysis Platform Combining the Microfluidic Devices with ESI-Q-TOF-MS -- Microfluidic Device with Integrated Porous Membrane for Cell Sorting and Separation -- Cell Co-culture and Signaling Analysis Based on Microfluidic Devices Coupling with ESI-Q-TOF-MS.
  note: by Huibin Wei.
  subject:
    topic: Chemistry
  subject:
    topic: Analytical chemistry
  subject:
    topic: Mass spectrometry
  subject:
    topic: Cell biology
  subject:
    topic: Nanotechnology
  subject:
    topic: Chemistry
  subject:
    topic: Mass Spectrometry
  subject:
    topic: Nanotechnology and Microengineering
  subject:
    topic: Cell Biology
  subject:
    topic: Analytical Chemistry
  classification: QD96.M3
  classification: 543.65
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Springer Theses, Recognizing Outstanding Ph.D. Research
  identifier: 9783642323591
  identifier: http://dx.doi.org/10.1007/978-3-642-32359-1
  record info:
    record creation date: 121026
    record change date: 20151204162830.0
    record identifier: 978-3-642-32359-1