rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics
  name:
    name part: Kim, Hae Won.
    role:
      role term: editor.
  name:
    name part: Greenburg, A. Gerson.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXIII, 746 p. 130 illus., 77 illus. in color. online resource.
  abstract: Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.
  table of contents: Brief historical account of HBOC development -- Physiology of respiration -- Oxygen transport to tissues -- Pathophysiology of acute anemia -- Global blood safety and need for safe blood supply -- Blood transfusion and its limitations -- Scientific basis and design of HBOCs -- HBOCs: a regulatory perspective -- Current HBOC products in development -- Clinical indications and clinical trials of HBOCs -- HBOCs and adverse events observed in clinical trials -- HBOC-mediated vasoactivity and hypertension -- HBOC and oxygen and nitrogen radical mediated toxicity -- HBOCs and clinical laboratory interference -- Animal models for HBOC studies -- New emerging Technologies for universal RBCs -- Future prospects.
  note: edited by Hae Won Kim, A. Gerson Greenburg.
  subject:
    topic: Materials science
  subject:
    topic: Molecular biology
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Hematology
  subject:
    topic: Biomaterials
  subject:
    topic: Materials Science
  subject:
    topic: Biomaterials
  subject:
    topic: Molecular Medicine
  subject:
    topic: Medicinal Chemistry
  subject:
    topic: Hematology
  classification: R857.M3
  classification: 620.11
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783642407178
  identifier: http://dx.doi.org/10.1007/978-3-642-40717-8
  record info:
    record creation date: 131218
    record change date: 20151103141120.0
    record identifier: 978-3-642-40717-8