rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Nucleic Acids in the Gas Phase
  name:
    name part: Gabelica, Valérie.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 287 p. 142 illus., 70 illus. in color. online resource.
  abstract: This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life. This volume introduces techniques used to investigate the properties of nucleic acids in the absence of solvent. It highlights the specificities pertaining to the studies of nucleic acids, although some of the techniques can similarly be applied to the study of other biomolecules, like proteins. The first part of the book introduces the techniques, from the transfer of nucleic acids to the gas-phase, to their detailed physico-chemical investigation. Each chapter is devoted to a specific molecular property, and illustrates how various approaches (experimental and theoretical) can be combined for the interpretation. The second part of the book is devoted to applying the gas-phase approaches to solve specific questions related to the biophysics, biochemistry or pharmacology of nucleic acids.
  table of contents: Introduction: Why study Nucleic Acids in vacuo? -- Transferring Nucleic Acids to the Gas Phase -- Structure of Nucleic Acids in the Gas Phase -- Interactions between Nucleic Acid Ions and Electrons and Photons -- Gas-phase Spectroscopy of Nucleic Acids -- Fragmentation Reactions of Nucleic Acid Ions in the Gas Phase -- Characterization of Ribonucleic Acids and their Modifications by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry -- Quantification of DNA Damage using Mass Spectrometry Techniques -- Ligand Binding to Nucleic Acids -- MS-based Approaches for Nucleic Acid Structural Determination.
  note: edited by Valérie Gabelica.
  subject:
    topic: Chemistry
  subject:
    topic: Mass spectrometry
  subject:
    topic: Spectroscopy
  subject:
    topic: Bioorganic chemistry
  subject:
    topic: Physical chemistry
  subject:
    topic: Nucleic acids
  subject:
    topic: Biophysics
  subject:
    topic: Biological physics
  subject:
    topic: Chemistry
  subject:
    topic: Mass Spectrometry
  subject:
    topic: Nucleic Acid Chemistry
  subject:
    topic: Biophysics and Biological Physics
  subject:
    topic: Spectroscopy/Spectrometry
  subject:
    topic: Bioorganic Chemistry
  subject:
    topic: Physical Chemistry
  classification: QD96.M3
  classification: 543.65
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Physical Chemistry in Action
  identifier: 9783642548420
  identifier: http://dx.doi.org/10.1007/978-3-642-54842-0
  record info:
    record creation date: 140728
    record change date: 20151030101755.0
    record identifier: 978-3-642-54842-0