rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Vaccine Analysis: Strategies, Principles, and Control
  name:
    name part: Nunnally, Brian K.
    role:
      role term: editor.
  name:
    name part: Turula, Vincent E.
    role:
      role term: editor.
  name:
    name part: Sitrin, Robert D.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 665 p. 124 illus., 76 illus. in color. online resource.
  abstract: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
  table of contents: Live Attenuated Viral Vaccines -- Inactivated Viral Vaccines -- Recombinant Virus Like Particle Protein Vaccines -- Analysis of influenza vaccines -- Live-attenuated and inactivated whole-cell bacterial vaccines -- Analytical control strategy of bacterial subunit vaccines -- Bacterial Polysaccharide Vaccines: Analytical Perspectives -- Glycoconjugate vaccines -- Vaccines in research and development: new production platforms and new biomolecular entities for new needs -- Role of Analytics In Viral Safety -- Deep Sequencing Applications for Vaccine Development and Safety -- Quality-by-design: As related to analytical concepts, control and qualification -- Vaccine Potency Assays -- Establishing a Shelf-life and Setting Lot-release Specifications -- Vaccine Reference Standards -- Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements -- Dendritic cell targeting vaccines.
  note: edited by Brian K. Nunnally, Vincent E. Turula, Robert D. Sitrin.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Vaccines
  subject:
    topic: Medical biochemistry
  subject:
    topic: Biomedicine
  subject:
    topic: Vaccine
  subject:
    topic: Immunology
  subject:
    topic: Medical Biochemistry
  classification: RM281
  classification: QR189-189.5
  classification: 615.372
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783662450246
  identifier: http://dx.doi.org/10.1007/978-3-662-45024-6
  record info:
    record creation date: 141127
    record change date: 20151204143814.0
    record identifier: 978-3-662-45024-6