rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Essentials of Single-Cell Analysis
    sub title: Concepts, Applications and Future Prospects
  name:
    name part: Tseng, Fan-Gang.
    role:
      role term: editor.
  name:
    name part: Santra, Tuhin Subhra.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: gw
    date issued: 2016
    edition: 1st ed. 2016.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 414 p. 142 illus., 127 illus. in color. online resource.
  abstract: This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA.
  table of contents: Single Cell Behavioral Assays for Heterogeneity Studies -- Systems biology in single cells -- Electroporation for single cell analysis -- Microinjection for single cell analysis -- Optical tools for single cell manipulation and analysis -- Optoelectrokinetic manipulation for cell analysis -- Continuous micro/nano-fluidic devices for single cell analysis -- Single Cell Mechanical Properties: Label-Free Biomarkers for Cell Status Evaluation -- Cytometry of single cells for biology and biomedicine -- Single cell genomics and epigenomics -- Single cell Metabolomics -- Applications of cell based drug delivery systems: use of single cell assay -- Applications of Single Cell Sequencing in Cancer -- Single Cell Characterization of Microalgal Lipid Contents with Confocal Raman Microscopy -- Single Differentiated Neurons from Pluripotent Embryonic Stem Cells: Motor Protein Modelling and Neurodegenerative Disease.
  note: edited by Fan-Gang Tseng, Tuhin Subhra Santra.
  subject:
    topic: Engineering
  subject:
    topic: Biotechnology
  subject:
    topic: Bioinformatics
  subject:
    topic: Cell biology
  subject:
    topic: Biomedical engineering
  subject:
    topic: Engineering
  subject:
    topic: Biomedical Engineering
  subject:
    topic: Microengineering
  subject:
    topic: Bioinformatics
  subject:
    topic: Biological and Medical Physics, Biophysics
  subject:
    topic: Cell Biology
  classification: R856-857
  classification: 610.28
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Series in BioEngineering
  identifier: 9783662491188
  identifier: http://dx.doi.org/10.1007/978-3-662-49118-8
  record info:
    record creation date: 160121
    record change date: 20160927110947.0
    record identifier: 978-3-662-49118-8