rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Interaction of Immune and Cancer Cells
  name:
    name part: Klink, Magdalena.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: au
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: X, 263 p. 21 illus., 17 illus. in color. online resource.
  abstract: The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and describe in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for scientists and medical doctors working and/or lecturing in the field of cancer research and immunology.
  table of contents: Immune cells within tumor microenvironment -- Tumor-stroma interaction and cancer progression -- The role of tumor associated macrophages (TAMs) in tumor progression -- Dendritic cells dysfunction and tumor progression -- Myeloid-derived suppressor cells (MDSC) and tumor growth -- Tumor-infiltrating lymphocytes and their role in solid tumor progression -- Polymorphonuclear neutrophils and tumor: friend or foe? -- Cancer immunosurveillance and immunoediting -- Adoptive T cell immunotherapy – Perfecting self-defense -- Monoclonal antibodies to CTLA4 with focus on ipilimumab.
  note: edited by Magdalena Klink.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Immunology
  subject:
    topic: Vaccines
  subject:
    topic: Molecular biology
  subject:
    topic: Cytokines
  subject:
    topic: Growth factors
  subject:
    topic: Biomedicine
  subject:
    topic: Immunology
  subject:
    topic: Cancer Research
  subject:
    topic: Vaccine
  subject:
    topic: Cytokines and Growth Factors
  subject:
    topic: Molecular Medicine
  classification: QR180-189.5
  classification: 616.079
  related item:
    title info:
      title: Springer eBooks
  identifier: 9783709113004
  identifier: http://dx.doi.org/10.1007/978-3-7091-1300-4
  record info:
    record creation date: 131125
    record change date: 20151204152933.0
    record identifier: 978-3-7091-1300-4