rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases
  name:
    name part: Hrckova, Gabriela.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Velebny, Samuel.
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: au
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 125 p. 19 illus., 8 illus. in color. online resource.
  abstract: The natural world with a large number of terrestrial and marine plants and lower organisms is a great source of bioactive compounds historically used as remedies in various diseases. Within the last decade, such compounds became more attractive targets for pharmacologists and the pharmaceutical industry in drug development projects. This volume presents the pharmacological potential of chemically defined natural compounds obtained from plants, fungi, algae and cyanobacteria with antiparasitic activity, that have been tested against various endo-parasitic protozoan and helminth species. Additionally, the advantages of combined therapy using antiparasitic drugs and natural compounds with selected specific activity are reviewed and explained in the context of host pathology and immunosuppression induced by the parasites. The conclusions of this new book give suggestions for further non-empirical drug development and discuss perspectives of alternative approaches to therapy of parasitic diseases.
  table of contents: Protozoan infections, pathology and therapy -- Current antiprotozoan drugs and problem of resistance -- Natural compounds with direct antiprotozoal activity -- Natural compounds isolated from higher plants -- Bioactive compounds from lower terrestrial organisms -- Marine organisms – undiscovered source of the potential drugs -- Concluding remarks -- Parasitic helminthes of human and amimals: health impact and control -- Anthelmintic drugs – efficacy, side effects and resistance -- Natural compounds with direct anthelmintic activity -- Anthelmintic potential of higher plants -- Lower terrestrial and marine organisms in anthelmintic drug discovery -- Concluding remarks -- Combined therapy of parasitic infections using substances from natural sources -- Host pathology and immunosuppression during parasitic infections -- Natural compounds with immunomodulatory effects -- Natural compounds with antioxidant and other host-protecting activities -- Summary: perpectives and possibilities in drug discovery from natural sources.
  note: by Gabriela Hrckova, Samuel Velebny.
  subject:
    topic: Medicine
  subject:
    topic: Parasitology
  subject:
    topic: Pharmacology
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Parasitology
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: SpringerBriefs in Pharmaceutical Science & Drug Development
  identifier: 9783709113257
  identifier: http://dx.doi.org/10.1007/978-3-7091-1325-7
  record info:
    record creation date: 121213
    record change date: 20151204162457.0
    record identifier: 978-3-7091-1325-7