rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Natural Compounds as Drugs Volume I
  name:
    name part: Petersen, Frank.
    role:
      role term: editor.
  name:
    name part: Amstutz, René.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: sz
    date issued: 2008
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 372 p. online resource.
  abstract: The use of drug substances derived from plants, fungi, bacteria, and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market. Within the fast developing discipline of molecular biology, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors. This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
  table of contents: Mother Nature’s gifts to diseases of man: the impact of natural products on anti-infective, anticholestemics and anticancer drug discovery -- Drug discovery and development with plant-derived compounds -- Evolutionary mechanisms underlying secondary metabolite diversity -- Biodiversity, chemical diversity and drug discovery -- High impact technologies for natural products screening -- Virtual screening for the discovery of bioactive natural products -- Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentation -- Nutritional and engineering aspects of microbial process development -- Natural products from plant cell cultures.
  note: edited by Frank Petersen, René Amstutz.
  subject:
    topic: Medicine
  subject:
    topic: Pharmacology
  subject:
    topic: Biochemistry
  subject:
    topic: Biomedicine
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Biochemistry, general
  classification: RM1-950
  classification: 615
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Progress in Drug Research ; 65
  identifier: 9783764381172
  identifier: http://dx.doi.org/10.1007/978-3-7643-8117-2
  record info:
    record creation date: 100301
    record change date: 20151204150441.0
    record identifier: 978-3-7643-8117-2