rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: New Therapeutic Targets in Rheumatoid Arthritis
  name:
    name part: Tak, Paul-Peter.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: sz
    date issued: 2009
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 228 p. online resource.
  abstract: The volume focuses on therapeutic targets that were identified after TNF blockade and that have recently been registered or are currently under development for the treatment of rheumatoid arthritis. Each chapter discusses the biological rationale in great detail, including in vitro work and work in animal models, and where appropriate, results from clinical trials. The book is written by an international authorship of experts in this field. It is of interest to rheumatologists, immunologists, internists, investigators in immunology and rheumatology as well as the pharmaceutical industry.
  table of contents: B cell targets in rheumatoid arthritis -- Co-stimulatory pathways in the therapy of rheumatoid arthritis -- Immunobiology of IL-6 — Tocilizumab (humanised anti-IL-6 receptor antibody) for the treatment of rheumatoid arthritis -- Role of IL-1 in erosive arthritis, lessons from animal models -- Interleukin-15 -- IL-17 and Th17 cells, key players in arthritis -- Role of IL-18 in inflammatory diseases -- Chemokines and chemokine receptors -- Signaling pathways in rheumatoid arthritis -- Targeting oncostatin M in the treatment of rheumatoid arthritis -- Targeting the epigenetic modifications of synovial cells -- Perspectives in targeted therapy.
  note: edited by Paul-Peter Tak.
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Pharmacology
  subject:
    topic: Rheumatology
  subject:
    topic: Cell biology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Rheumatology
  subject:
    topic: Immunology
  subject:
    topic: Pharmacology/Toxicology
  subject:
    topic: Cell Biology
  classification: RC927-927.5
  classification: 616.723
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Progress in Inflammation Research
  identifier: 9783764382384
  identifier: http://dx.doi.org/10.1007/978-3-7643-8238-4
  record info:
    record creation date: 100301
    record change date: 20151204165706.0
    record identifier: 978-3-7643-8238-4