rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Neurodegeneration in Multiple Sclerosis
  name:
    name part: Filippi, Massimo.
    role:
      role term: editor.
  name:
    name part: Rovaris, Marco.
    role:
      role term: editor.
  name:
    name part: Comi, Giancarlo.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: it
    date issued: 2007
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XI, 236 p. online resource.
  abstract: In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic reliability and to monitor the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy as to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is dramatically changing our understanding of how MS causes irreversible disability. Written by world-renowned scientists, the volume is indispensable for anybody working in this field.
  table of contents: Background -- Neuropathological Advances in Multiple Sclerosis -- Neurophysiology -- MRI Techniques to Assess Neurodegeneration -- Atrophy -- T1 Black Holes and Gray Matter Damage -- Magnetization Transfer Imaging -- Perfusion MR I -- Diffusion-Weighted Imaging -- Proton MR Spectroscopy -- Functional MRI -- Evaluation of MRI Outcomes -- Validation of MRI Surrogates -- Defining Responders and Non-responders -- Predictive Models in Multimodal Imaging -- Lessons from Other Neurodegenerative Diseases -- Alzheimer’s Disease -- Other Neurodegenerative Conditions -- Incorporation of Other Biomarkers -- Designing MS Trials for Neurodegeneration -- Critical Review of Existing Trials -- Design for the Next Trials of Neurodegeneration.
  note: edited by Massimo Filippi, Marco Rovaris, Giancarlo Comi.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Radiology
  subject:
    topic: Neuroradiology
  subject:
    topic: Nuclear medicine
  subject:
    topic: Neurology
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Neurology
  subject:
    topic: Neurosciences
  subject:
    topic: Imaging / Radiology
  subject:
    topic: Neuroradiology
  subject:
    topic: Nuclear Medicine
  classification: RC346-429.2
  classification: 616.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Topics in Neuroscience
  identifier: 9788847003910
  identifier: http://dx.doi.org/10.1007/978-88-470-0391-0
  record info:
    record creation date: 100301
    record change date: 20151204173521.0
    record identifier: 978-88-470-0391-0