rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Supramolecular Chemistry
    sub title: From Biological Inspiration to Biomedical Applications
  name:
    name part: Cragg, Peter J.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XV, 260 p. online resource.
  abstract: Supramolecular chemistry is often described as the study of chemistry beyond the simple molecular level yet it is often forgotten how many of the pioneering su-pramolecular chemists looked to molecular biology for their ideas. The search for an aldolase enzyme mimic, the discovery of crown ethers that transported potas-sium as efficiently as valinomycin, and the synthesis of an antitubercular com-pound that resembled a transmembrane protein, all point to a biological inspira-tion. Since the field emerged in the last quarter of the 20th Century, advances in the synthesis of multifunctional molecules, coupled to a greater understanding of biological processes at the molecular level, have led supramolecular chemists to design compounds that not only mimic those in Nature but also have diagnostic and therapeutic applications. The book opens with an overview of supramolecular chemistry. In subsequent chapters parallels are drawn with biological phenomena: the formation of proteins and other biomolecules, the evolution of cells, and the design of channel-forming molecules and enzymes. The application of supramolecular principles to sensors and magic bullet therapies is explained and the future of supramolecular therapeutics is considered. The exciting combination of supramolecular chemistry and nanotechnology is discussed together with the likelihood that nanoengineered smart materials could one day circulate in the body to treat patients before they became aware of any symptoms. Supramolecular Chemistry: From Biological Inspiration to Biomedical Applications is aimed at postgraduates working at the chemistry/life science interface and final year undergraduate advanced options in supramolecular chemistry. It is hoped that it will also be of value to academics and professionals interested in the relevance of supramolecular chemistry to biology and vice versa.
  table of contents: An Introduction to Supramolecular Chemistry -- Supramolecular Chemistry and the Life Sciences -- Artificial Cells -- Supramolecular Enzyme Mimics -- Natural and Synthetic Transmembrane Channels -- Diagnostic Applications -- Supramolecular Therapeutics -- Bionanotechnology, Nanomedicine and the Future.
  note: by Peter J. Cragg.
  subject:
    topic: Chemistry
  subject:
    topic: Pharmacy
  subject:
    topic: Molecular biology
  subject:
    topic: Organic chemistry
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Chemistry
  subject:
    topic: Medicinal Chemistry
  subject:
    topic: Molecular Medicine
  subject:
    topic: Pharmacy
  subject:
    topic: Organic Chemistry
  subject:
    topic: Biomedicine general
  classification: RS400-431
  classification: 615.19
  related item:
    title info:
      title: Springer eBooks
  identifier: 9789048125821
  identifier: http://dx.doi.org/10.1007/978-90-481-2582-1
  record info:
    record creation date: 100825
    record change date: 20151125191926.0
    record identifier: 978-90-481-2582-1