rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: Myelodysplastic Syndromes
  name:
    name part: Várkonyi, Judit.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIII, 286 p. online resource.
  abstract: Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged 70 or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia. In the past decade much progress had been made; we know more on the disease pathology, there is more emphasis on the care and more targeted therapy had been invested. Athors provide updated knowledge in this book on all clinically important aspects of the disease. Hot topics of our days are discussed in chapters by outstanding and well known scientists from all over the world. We would offer this product both for medical students and postgraduates as well as for all who are interested in this very exciting and fast progressing field of hematology. With this work authors should call attention on the disease for decision makers in healt care systems as well. .
  table of contents: 1. PREFACE -- 2. The history of the Myelodysplastic Syndromes -- 3. Susceptibility to MDS: DNA repair and detoxification genes -- 4. Myelodysplastic syndromes/neoplasms: Morphological and Immunohistochemical features and standard evaluation -- 5. Diagnostic Criteria and Classification of Myelodysplastic Syndromes -- 6. Cytogenetics of MDS -- 7. Molecular changes in myelodysplastic syndrome -- 8. Prognostic Scoring in MDS -- 9. Flow Cytometry in Myelodysplastic Syndromes -- 10. MDS as an Autoimmune Process -- 11. The Myelodysplastic Overlap Syndromes -- 12. Iron and copper Metabolismin the Myelodysplastic Syndromes -- 13. Pathogenesis and Management of Iron Overload in MDS -- 14. Cytokines in MDS. Abnormalities and treatment -- 15. Therapeutic Modalities and new molecular targets in MDS -- 16. Haematopoietic Stem Cell Transplantation in MDS for Adults -- 17. JMML and Myelodysplastic Syndrome in children.
  note: edited by Judit Várkonyi.
  subject:
    topic: Medicine
  subject:
    topic: Hematology
  subject:
    topic: Biomedicine
  subject:
    topic: Biomedicine general
  subject:
    topic: Hematology
  subject:
    topic: Medicine/Public Health, general
  classification: R-RZ
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  identifier: 9789400704404
  identifier: http://dx.doi.org/10.1007/978-94-007-0440-4
  record info:
    record creation date: 110322
    record change date: 20150520194535.0
    record identifier: 978-94-007-0440-4