rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Lactoferrin and its Role in Wound Healing
  name:
    name part: Takayama, Yoshiharu.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 108 p. online resource.
  abstract: “Lactoferrin and its Role in Wound Healing” summarizes the recent advances of molecular mechanisms of wound healing. It is a complex physiological process that requires the regulation of different types of cells such as immune cells, keratinocytes, fibroblasts, and endothelial cells. Lactoferrin was first identified as an iron-binding glycoprotein abundantly found in milk. It has been considered to play important roles in host defense, since lactoferrin shows broad spectrum of anti-bacterial and anti-viral activities, arising from its iron-chelating property. Furthermore, lactoferrin can regulate the function of innate and adaptive immune cells and exhibits immuno-modulating properties. These activities of lactoferrin implicate that potential use of lactoferrin as a wound healing agent. In addition, this book shows that lactoferrin is a potent regulator of dermal fibroblasts and epidermal keratinocytes, and promotes skin or corneal epithelial wound healing by increasing their proliferation, migration or deposition of extracellular matrix (ECM) components such as collagen and hyaluronan. This book provides the scientific background on use of lactoferrin as a wound healing agent. Indeed, lactoferrin exerts its biological effects by binding to specific lactoferrin receptors on target cells. This book also covers the in-depth information on roles of lactoferrin as a signaling molecule.
  note: by Yoshiharu Takayama.
  subject:
    topic: Medicine
  subject:
    topic: Human physiology
  subject:
    topic: Proteins
  subject:
    topic: Cell biology
  subject:
    topic: Cell membranes
  subject:
    topic: Biomedicine
  subject:
    topic: Biomedicine general
  subject:
    topic: Human Physiology
  subject:
    topic: Cell Biology
  subject:
    topic: Protein Science
  subject:
    topic: Receptors
  subject:
    topic: Membrane Biology
  classification: R-RZ
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  identifier: 9789400724679
  identifier: http://dx.doi.org/10.1007/978-94-007-2467-9
  record info:
    record creation date: 111024
    record change date: 20151125231849.0
    record identifier: 978-94-007-2467-9