rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
  name:
    name part: Toman, Rudolf.
    role:
      role term: editor.
  name:
    name part: Heinzen, Robert A.
    role:
      role term: editor.
  name:
    name part: Samuel, James E.
    role:
      role term: editor.
  name:
    name part: Mege, Jean-Louis.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XIV, 406 p. online resource.
  abstract: Over 20 years have elapsed since publication of the seminal two volume series entitled Q Fever: The Biology of Coxiella burnetii (edited by J. C. Williams and H. A. Thompson) and Q fever: The Disease (edited by T. J. Marrie) that described the current state of Coxiella burnetii research. The ensuing years have brought the post-genomic era and accompanying technologies that have catalyzed major advances in the field, including milestones discoveries of genetic transformation and host cell-free growth of this former obligate intracellular bacterium. Understanding how the bacterium resists the degradative functions of vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. The book covers the current state-of-the-art knowledge in the selected fields of C. burnetii/Q fever research. Coxiella has matured from a niche organism, investigated by a handful of laboratories worldwide, to a model system to study macrophage parasitism, developmental biology, host-pathogen interactions, and immune evasion/modulation.
  note: edited by Rudolf Toman, Robert A. Heinzen, James E. Samuel, Jean-Louis Mege.
  subject:
    topic: Medicine
  subject:
    topic: Genetic engineering
  subject:
    topic: Infectious diseases
  subject:
    topic: Bioinformatics
  subject:
    topic: Cell biology
  subject:
    topic: Biomedicine
  subject:
    topic: Biomedicine general
  subject:
    topic: Cell Biology
  subject:
    topic: Genetic Engineering
  subject:
    topic: Infectious Diseases
  subject:
    topic: Computational Biology/Bioinformatics
  classification: R-RZ
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Advances in Experimental Medicine and Biology, 984
  identifier: 9789400743151
  identifier: http://dx.doi.org/10.1007/978-94-007-4315-1
  record info:
    record creation date: 120618
    record change date: 20151125151018.0
    record identifier: 978-94-007-4315-1