rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Tight Junctions in Cancer Metastasis
  name:
    name part: Martin, Tracey A.
    role:
      role term: editor.
  name:
    name part: Jiang, Wen G.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 313 p. online resource.
  abstract: There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.
  table of contents: Preface -- The molecular aspects of Tight junctions -- The distribution of tight junctions and junctional proteins in the body -- Methodologies in investigation tight junctions -- Vascular permeability and drug delivery -- Tight junctions, BBB and brain metastasis -- Tight junctions and bladder cancer metastasis -- Tight Junctions and colorectal cancer therapies -- Tight junctions in breast cancer -- Regulation of tight junctions for therapeutic advantages -- Overcoming tight junctional permeability in cerebral metastasis -- CL-5 and cancer metastasis -- Intracellular signalling in TJ and AJ -- ROCK and TJ -- Index.
  note: edited by Tracey A. Martin, Wen G. Jiang.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Oncology
  subject:
    topic: Cell biology
  subject:
    topic: Cell membranes
  subject:
    topic: Biomedicine
  subject:
    topic: Biomedicine general
  subject:
    topic: Cancer Research
  subject:
    topic: Oncology
  subject:
    topic: Cell Biology
  subject:
    topic: Membrane Biology
  classification: R-RZ
  classification: 610
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Cancer Metastasis - Biology and Treatment, 19
  identifier: 9789400760288
  identifier: http://dx.doi.org/10.1007/978-94-007-6028-8
  record info:
    record creation date: 130228
    record change date: 20151030091543.0
    record identifier: 978-94-007-6028-8