rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Interrelations between Essential Metal Ions and Human Diseases
  name:
    name part: Sigel, Astrid.
    role:
      role term: editor.
  name:
    name part: Sigel, Helmut.
    role:
      role term: editor.
  name:
    name part: Sigel, Roland K.O.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XXXVII, 573 p. 103 illus., 28 illus. in color. online resource.
  abstract: MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.
  table of contents: Metal Ions and Infectious Diseases. An Overview from the Clinic -- Sodium and Potassium in Health and Disease -- Magnesium in Health and Disease -- Calcium in Health and Disease -- Vanadium. Its Role for Humans -- Chromium: Is It Essential, Pharmacologically Relevant or Toxic?- Manganese in Health and Disease -- Iron: Effect of Deficiency and Overload -- Cobalt: Its Role in Health and Disease -- Nickel and Human Health -- Copper: Effects of Deficiency and Overload -- Zinc and Human Disease -- Molybdenum in Human Health and Disease -- Silicon: The Health Benefits of a Metalloid -- Arsenic. Can this Toxic Metalloid Sustain Life? -- Selenium. Role of the Essential Metalloid in Health.
  note: edited by Astrid Sigel, Helmut Sigel, Roland K.O. Sigel.
  subject:
    topic: Life sciences
  subject:
    topic: Chemistry
  subject:
    topic: Life Sciences
  subject:
    topic: Life Sciences, general
  subject:
    topic: Biomedicine general
  subject:
    topic: Chemistry/Food Science, general
  classification: QH301-705
  classification: 570
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Metal Ions in Life Sciences, 13
  identifier: 9789400775008
  identifier: http://dx.doi.org/10.1007/978-94-007-7500-8
  record info:
    record creation date: 140127
    record change date: 20151204145017.0
    record identifier: 978-94-007-7500-8