rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Experimental Metastasis: Modeling and Analysis
  name:
    name part: Malek, Anastasia.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: ne
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 210 p. 71 illus., 32 illus. in color. online resource.
  abstract: Metastatic dissemination remains a main cause for cancer related deaths. Investigation of the molecular mechanisms of the metastatic process presents an important area of cancer research and may provide clinical oncologists with new methods to prevent and manage cancer dissemination. Availability of adequate experimental models is an essential requirement of the productive investigation. Over the many years of cancer research, plenty of model systems (in vitro and in vivo) were created to reproduce certain steps or to estimate certain aspects of metastatic process. Currently right selection and correct application of the experimental models as well as analytic technique may present a challenge. This book provide with guideline information about experimental modelling and analysis of the metastatic process. The structure of the book reflects clinical aspects: pathway and area of the metastatic dissemination. Thus, first part of book is devoted to local, mainly via lymph system, spread of head and neck, breast and pancreatic cancers. Second part is about distant, via blood stream, dissemination into brain and lung (most often sites of metastatic lesion regardless the primary tumour issue). Third part includes chapter describing methods of modelling and study specific metastatic pathways: via portal vein system and through serous cavities. Any chapter is introduced by short review of clinical/biological aspects of the specific metastatic process, provides with description of relevant laboratory techniques, supplemented with representative illustrations and extended references list. Theoretic aspects of cancer dissemination and mathematic approaches to model metastatic spread of tumour are reviewed in the last chapter. Chapters of the book are written by leading specialists in certain areas of metastatic cancer research, therefore the book presents a comprehensive guide for researchers and may be helpful for clinical oncologists.
  table of contents: Preface -- Introduction -- Head and neck cancer -- Breast cancer invasion and metastasis -- Mouse models of pancreatic cancer -- Brain Metastasis -- Lung metastasis -- Liver Metastases -- Malignant pleural effusion -- Mathematic modeling of metastatic process. Index.
  note: edited by Anastasia Malek.
  subject:
    topic: Medicine
  subject:
    topic: Cancer research
  subject:
    topic: Laboratory medicine
  subject:
    topic: Cell culture
  subject:
    topic: Animal models in research
  subject:
    topic: Biomedicine
  subject:
    topic: Cancer Research
  subject:
    topic: Laboratory Medicine
  subject:
    topic: Animal Models
  subject:
    topic: Cell Culture
  classification: RC261-271
  classification: 614.5999
  related item:
    title info:
      title: Springer eBooks
  identifier: 9789400778351
  identifier: http://dx.doi.org/10.1007/978-94-007-7835-1
  record info:
    record creation date: 131202
    record change date: 20151204175431.0
    record identifier: 978-94-007-7835-1