rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Moyamoya Disease Explored Through RNF213
    sub title: Genetics, Molecular Pathology, and Clinical Sciences
  name:
    name part: Koizumi, Akio.
    role:
      role term: editor.
  name:
    name part: Nagata, Kazuhiro.
    role:
      role term: editor.
  name:
    name part: Houkin, Kiyohiro.
    role:
      role term: editor.
  name:
    name part: Tominaga, Teiji.
    role:
      role term: editor.
  name:
    name part: Miyamoto, Susumu.
    role:
      role term: editor.
  name:
    name part: Kure, Shigeo.
    role:
      role term: editor.
  name:
    name part: Tournier-Lasserve, Elizabeth.
    role:
      role term: editor.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: si
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 185 p. 36 illus., 22 illus. in color. online resource.
  abstract: This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to the study of the disease. Moyamoya Disease Explored Through RNF213 is an indispensable resource for both beginning and experienced researchers, pediatricians, neurologists, and neurosurgeons who are seeking comprehensive information on adult and childhood stroke.
  table of contents: Part I: Prologue -- 1. A prologue to moyamoya disease and RNF213 -- 2. Concept of moyamoya Disease -- Part II: Genetic Epidemiology -- 3. Molecular Epidemiology in East Asian Countries and in the World -- Part III: Biochemistry, Function and Molecular Pathology -- 4. Molecular Biology of Mysterin/RNF213 -- 5. Physiological Role of Mysterin/RNF213 in Zebrafish -- 6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction -- 7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice -- 8. RNF213 and Circulating Factors in Patients with Moyamoya Disease -- 9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes -- Part IV: Clinical Management 10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management -- 11. Significance of RNF213 in Clinical Management in Japan -- 12. Significance of RNF213 in Clinical Management in China -- 13. The Different Forms of Moyamoya Disease and Their Clinical Management -- 14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease -- Part V: Epilogue -- Future Clinical Perspectives on RNF213 in Moyamoya Disease.
  note: edited by Akio Koizumi, Kazuhiro Nagata, Kiyohiro Houkin, Teiji Tominaga, Susumu Miyamoto, Shigeo Kure, Elizabeth Tournier-Lasserve.
  subject:
    topic: Medicine
  subject:
    topic: Public health
  subject:
    topic: Neurology
  subject:
    topic: Neurosurgery
  subject:
    topic: Medicine & Public Health
  subject:
    topic: Neurology
  subject:
    topic: Neurosurgery
  subject:
    topic: Public Health
  classification: RC346-429.2
  classification: 616.8
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Current Topics in Environmental Health and Preventive Medicine
  identifier: 9789811027116
  identifier: http://dx.doi.org/10.1007/978-981-10-2711-6
  record info:
    record creation date: 170221
    record change date: 20170221092656.0
    record identifier: 978-981-10-2711-6