rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Regulation of Signal Transduction in Human Cell Research
  name:
    name part: Shinomiya, Nariyoshi.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: Kataoka, Hiroaki.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: Xie, Qian.
    role:
      role term: editor.
    role:
      role term: edt
    role:
      role term: http://id.loc.gov/vocabulary/relators/edt
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: si
    date issued: 2018
    edition: 1st ed. 2018.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: VIII, 218 p. 49 illus., 41 illus. in color. online resource.
  abstract: This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.
  note: edited by Nariyoshi Shinomiya, Hiroaki Kataoka, Qian Xie.
  subject:
    topic: Oncology
  subject:
    topic: Medical biochemistry
  subject:
    topic: Cancer research
  subject:
    topic: Oncology
  subject:
    topic: Medical Biochemistry
  subject:
    topic: Cancer Research
  classification: RC254-282
  classification: 616.994
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Current Human Cell Research and Applications
  identifier: 9789811072963
  identifier: https://doi.org/10.1007/978-981-10-7296-3
  record info:
    record creation date: 180215
    record change date: 20191220125552.0
    record identifier: 978-981-10-7296-3