rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: CPP, Cell-Penetrating Peptides
  name:
    name part: Langel, Ülo.
    role:
      role term: creator
    role:
      role term: author.
    role:
      role term: aut
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  origin info:
    place:
      place term: si
    date issued: 2019
    edition: 1st ed. 2019.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    form: electronic resource
    reformatting quality: access
    form: remote
    extent: XII, 470 p. 25 illus., 17 illus. in color. online resource.
  abstract: In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field.
  table of contents: Classes and applications of CPP -- CPP functionalization -- Protein delivery and mimicry -- Targeting strategies -- Methods for detection and visualization of CPPs -- Methods for structural studies of CPPs -- Kinetics -- Toxicity and immune response -- Cell-translocation mechanisms of CPPs -- Clinical trials and commercialization using CPPs -- Therapeutic potential of CPPs.
  note: by Ülo Langel.
  subject:
    topic: Proteins
  subject:
    topic: Molecular biology
  subject:
    topic: Medicinal chemistry
  subject:
    topic: Protein Science
  subject:
    topic: Molecular Medicine
  subject:
    topic: Medicinal Chemistry
  classification: QD431-431.7
  classification: 572.6
  related item:
    title info:
      title: Springer eBooks
  identifier: 9789811387470
  identifier: https://doi.org/10.1007/978-981-13-8747-0
  record info:
    record creation date: 190603
    record change date: 20191025012459.0
    record identifier: 978-981-13-8747-0