rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Protein engineering
  name:
    name part: Robertson, Dan E.
  name:
    name part: Noel, Joseph P.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    place:
      place term: Boston
    publisher: Elsevier Academic Press
    date issued: ©2004
    date issued: 2004
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xxxvii, 413 pages, [16] pages of plates) : illustrations (some color).
  abstract: This MIE volume covers methods for a multitude of topics among which are computational methods, laboratory methods, enzyme optimization, binding proteins/antibodies, and screening technologies.
  table of contents: Section I. Methodology -- Gene site saturation mutagenesis : a comprehensive mutagenesis approach -- Single-stranded DNA family shuffling -- Module shuffling -- SCHEMA-guided protein recombination -- Staggered extension process in vitro DNA recombination -- Using incremental truncation to create libraries of hybrid enzymes -- Random multirecombinant polymerase chain reaction -- Gene library synthesis by structure-based combinatorial protein engineering -- New enzymes from combinatorial library modules -- Construction of protein fragment complementation libraries using incremental truncation -- Section II. Applications: optimization and screening -- GigaMatrix: a novel ultrahigh throughput protein optimization and discovery platform -- High throughput microplate screens for directed protein evolution -- Periplasmic expression as a basis for whole cell kinetic screening of unnatural enzyme reactivities -- Engineering the thermotolerance and pH optimum of family 11 xylanases by site-directed mutagenesis -- Screening for oxidative resistance -- Consensus-based engineering of protein stability: from intrabodies to thermostable enzymes -- Improving the functional expression of N-Carbamoylase by directed evolution using the green fluorescent protein fusion reporter system -- Section III. Applications: directed evolution of enzymatic function -- Directed evolution of lipases and esterases -- Protein engineering of the cytochrome P450 monooxygenase from bacillus megaterium -- Directed evolution of aldolases -- Changing the enantioselectivity of enzymes by directed evolution -- Control of stereoselectivity in phosphotriesterase -- Section IV. Applications: evolution of biosynthetic pathways -- Manipulation and analysis of polyketide synthases -- Reactions catalyzed by mature and recombinant nonribosomal peptide synthetases -- Engineering carotenoid biosynthetic pathways -- Section V. Devices, antibodies, and vaccines -- Directed evolution of bacteriorhodopsin for device appli…
  note: edited by Dan E. Robertson, Joseph P. Noel.
  note: Includes bibliographical references and indexes.
  subject:
    topic: Protein engineering
  subject:
    topic: Proteins
    topic: Synthesis
  subject:
    topic: Genetic engineering
  subject:
    topic: Proteins
    topic: Structure-activity relationships
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Biochemistry
  subject:
    topic: Genetic engineering
  subject:
    topic: Protein engineering
  subject:
    topic: Proteins
    topic: Structure-activity relationships
  subject:
    topic: Proteins
    topic: Synthesis
  subject:
    topic: Proteine
  subject:
    topic: Enzymologie
  subject:
    topic: Genetic Engineering [MESH]
  subject:
    topic: Protein Conformation [MESH]
  subject:
    topic: Proteins
    topic: genetics [MESH]
  classification: QP601 .M49 vol. 388
  classification: TP248.65.P76
  classification: 572/.7
  classification: QU 55
  related item:
    title info:
      title: Protein engineering
    origin info:
      publisher: Amsterdam ; Boston : Elsevier Academic Press, ©2004
    identifier: (OCoLC)56137371
  related item:
    title info:
      title: Methods in enzymology ; v. 388
  identifier: 9780080497259
  identifier: 008049725X
  identifier: 0121827933
  identifier: 9780121827939
  identifier: 1281011541
  identifier: 9781281011541
  identifier: https://www.sciencedirect.com/science/bookseries/00766879/388
  record info:
    record content source: SCPER
    record creation date: 040812
    record change date: 20180501121920.0
    record identifier: ocn326626539
    language of cataloging:
      language term: eng